The First Century of Ketenes(1905-2005):The Birth of a Versatile Family of Reactive Intermediates

摘要

Organic reactive intermediates are the species involved in multistep organic reactions,and the beginning of the 20th century saw convincing experimental evidence for these entities become available. The discovery by Gomberg in 1900 that triphenylmethyl chloride and zinc formed the stable triphenylmethyl radical(1)[Eq.(1)],was widely noted,and Gomberg narrowly missed the award of the Nobel prize for his discovery.