A Surface-Bound DNA Switch Driven by a Chemical Oscillator

摘要

The fabrication of autonomously moving molecular structures is one of the central challenges in the field of DNA nanodevices.[1] Some of the concepts introduced recently to achieve this goal rely on the sequence-dependent catalyticaction of DNA-modifying enzymes such as restriction endonucleases or nicking enzymes[2] while others use the catalytic power of DNA itself by incorporating DNA enzyme sequences into DNA devices.[3] Both approaches have also been used to realize autonomous molecular computers.