Prins Cyclizations in Au-Catalyzed Reactions of Enynes

摘要

The hydroxy- or alkoxycyclization of enynes I catalyzed by electrophilic transition-metal complexes usually takes place through cyclopropyl metal carbenes II,which react with nucleophiles R'OH to give intermediates III (Scheme 1).The reaction is then terminated by proto-demetalation of the alkenyl metal intermediate III to give IV.