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Emblica officinalis outcome on noise stress induced behavioural changes in wistar albino rats

机译:余甘子对噪声应激引起的白星病大鼠行为改变的影响

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摘要

Exposure to any kind of noise exceeding 90 dB is reported to be a stressor. This study focuses on whether Emblica officinalis supplement (333 mg/kg/b.wt) could avert the noise stress induced behavioural changes in Wistar albino rats. Noise stress animals were exposed to 100 dB (4 hr/day) for 15 days. When compared to control and E. officinalis treated animals, noise stress animals showed an increased immobilization, rearing, fecal bolus and marked decrease in ambulation and grooming in open field test, whereas in elevated plus maze, it showed a marked decrease in the number of open arm entry and percentage, time spent in open arm and percentage. Noise stress animals treated with E. officinalis showed improvement in all the above observations and recovered from the stress. The results imply that E. officinalis possesses anti-stressor property by reducing the noise stress induced alterations in behaviour, its effect might be due to the antioxidant property of E. officinalis.
机译:据报道,暴露于任何类型的超过90 dB的噪声都是一个压力源。这项研究的重点是Emblica officinalis补充剂(333 mg / kg / b.wt)是否可以避免Wistar白化病大鼠的噪声应激诱导的行为改变。噪声应激动物暴露于100 dB(4小时/天)下15天。与对照组和大肠埃希菌处理的动物相比,噪声应激动物在野外试验中显示出增加的固定性,饲养性,粪便推注性和行走和修饰的显着减少,而在高架迷宫中,其活动数量显着减少。张开双臂输入和百分比,张开双臂花费的时间和百分比。用厚朴大肠杆菌治疗的噪声应激动物在上述所有观察结果中均表现出改善,并从应激中恢复。结果表明,厚朴具有减少应激引起的行为变化的抗应激作用,其作用可能是由于厚朴具有抗氧化作用。

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