Effects of pH and Light Irradiation on Coenzyme Q_(10) Production Using Rhodobacter sphaeroides

摘要

To increase the level of CoQ_(10) production in mass culture, the effects of pH and light irradiation on CoQ_(10) production by Rhodobacter sphaeroides were investigated in a 1-L bioreactor. CoQ_(10) production was growth-associated, and the highest production of CoQ_(10) (1.69 mg/g dry cell) was obtained under uncontrolled pH; this production was 1.7 times higher than that obtained at controlled pH 7. Therefore, pH was a key factor affecting CoQ_(10) production. The effect of light irradiation on CoQ_(10) production was negligible. This result offers an advantage for mass production of CoQ_(10).