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Metal Complexes of Diisopropylthiourea: Synthesis Characterization and Antibacterial Studies

机译:二异丙基硫脲的金属配合物:合成表征和抗菌研究。

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摘要

Co(II), Cu(II), Zn(II) and Fe(III) complexes of diisopropylthiourea have been synthesized and characterized by elemental analyses, molar conductivity, magnetic susceptibility, FTIR and electronic spectroscopy. The compounds are non-electrolytes in solution and spectroscopic data of the complexes are consistent with 4-coordinate geometry for the metal(II) complexes and six coordinate octahedral for Fe(III) complex. The complexes were screened for their antibacterial activities against six bacteria: Escherichia coli, Pseudomonas auriginosa, Klebsiella pneumoniae, Bacillus cereus, Staphylococcus aureus and Bacillus pumilus. The complexes showed varied antibacterial activities and their minimum inhibitory concentrations (MICs) were determined.
机译:合成了二异丙基硫脲的Co(II),Cu(II),Zn(II)和Fe(III)配合物,并通过元素分析,摩尔电导率,磁化率,FTIR和电子光谱对其进行了表征。该化合物在溶液中为非电解质,配合物的光谱数据与金属(II)配合物的四坐标几何和六价八面体的铁(III)配合物一致。筛选复合物对六种细菌的抗菌活性:大肠杆菌,假单胞菌,肺炎克雷伯菌,蜡状芽孢杆菌,金黄色葡萄球菌和短小芽孢杆菌。该复合物显示出不同的抗菌活性,并确定了其最低抑菌浓度(MIC)。

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