Objective To analyze the clinical and ultrasonic features of pulmonary thrombosis embolism( PTE). Methods A total of 974 patients with PTE were collected in the First Affiliated Hospital of China Medical University from December 2010 to March 2015,and then gender,age,underlying disease and past medical history,clinical and ultrasonic features were retrospectively analyzed. Results Of the 974 patients,532 cases were male,442 cases were female;age varied from 16 to 93 years old,the median age was〔61(20)〕years old,and the median age of female was statistically significantly elder than that of male{〔62(17)〕vs. 〔61(23)〕,Z = - 2. 43,P < 0. 05}. Of the 974 patients,187 cases complicated with hypertension( accounting for 19. 20% ),146 cases treated by surgical operation( accounting for 14. 99% ),121 cases coexisted with malignant tumor( accounting for 12. 42% ),119 cases coexisted with coronary heart disease( accounting for 12. 22% ),92 cases coexisted with diabetes(accounting for 9. 45% ),68 cases coexisted with ischemic cerebrovascular disease (accounting for 7. 00% ),48 cases coexisted with connective tissue diseases(accounting for 4. 93% ),44 cases coexisted with trauma(accounting for 4. 52% ),43 cases coexisted with atrial fibrillation(accounting for 4. 41% ),25 cases coexisted with nephrotic syndrome(accounting for 2. 57% ),14 cases coexisted with heart valve disease(accounting for 1. 44% ),12 cases coexisted with lower limbs arteriosclerosis obliterans( accounting for 1. 23% ). Of the 974 patients,798 cases performed as dyspnea(accounting for 81. 93% ),321 cases performed as accelerated respiratory rate(accounting for 32. 96% ),while only 59 cases(accounting for 6. 06% )performed as typical triad of PTE(that is dyspnea,chest pain and hemoptysis). Of the 974 patients,690 cases received ultrasound examination for lower extremity deep vein,thereinto 363 cases( accounting for 52. 60% )found lower extremity deep venous thrombosis(LEDVT),327 cases did not(accounting for 47. 40% );496 cases received transthoracic and transesophageal echocardiography( TTE),thereinto 169 cases found signs of PTE( accounting for 34. 07% ),17 cases found intracardiac embolus;the sensitivity of TTE in diagnosing massive pulmonary embolism(MPE)was 60. 45% ,the specificity was 86. 96% . Conclusion The clinical features of PTE are not specific,the median age is 61 years old with gender difference;cardiac - cerebral vascular disease,surgical operation,malignant tumor,trauma,connective tissue diseases and nephrotic syndrome can increase the occurrence risk of PTE;ultrasound examination for lower extremity deep vein and TTE is helpful to timely find PTE.%目的：分析肺血栓栓塞症（PTE）患者的临床及超声检查特征。方法收集中国医科大学附属第一医院2010年12月—2015年3月收治的 PTE 住院患者974例，回顾性分析其性别、年龄、基础疾病及既往史、临床表现及超声检查特征等。结果本组974例患者中男532例，女442例；年龄16~93岁，中位年龄〔61（20）〕岁；女性患者中位年龄大于男性｛〔62（17）〕与〔61（23）〕，Z =-2.43，P <0.05｝。合并高血压者187例（占19.20%）、为外科手术术后者146例（占14.99%）、合并恶性肿瘤者121例（占12.42%）、合并冠心病者119例（占12.22%）、合并糖尿病者92例（占9.45%）、合并缺血性脑血管疾病者68例（占7.00%）、合并结缔组织疾病者48例（占4.93%）、合并创伤者44例（占4.52%）、合并心房颤动者43例（占4.41%）、合并肾病综合征者25例（占2.57%）、合并心脏瓣膜疾病者14例（占1.44%）、合并下肢动脉闭塞症者12例（占1.23%）。表现为呼吸困难者798例（占81.93%），表现为呼吸频率加快者321例（占32.96%），表现为典型 PTE“三联征（呼吸困难、胸痛、咯血）”者59例（占6.06%）。690例患者行下肢深静脉超声检查，发现下肢深静脉血栓形成（LEDVT）者363例（占52.60%），无 LEDVT 者327例（占47.40%）。496例患者行超声心动图（TTE）检查，其中169例（占34.07%）发现 PTE 直接征象，17例发现心内栓子；TTE 检查诊断大面积肺栓塞（MPE）的灵敏度为60.45%，特异度为86.96%。结论 PTE 临床表现缺乏特异性，患者中位年龄为61岁且存在性别差异，心脑血管疾病、外科手术、恶性肿瘤、创伤、结缔组织疾病及肾病综合征等均可增加 PTE 发生风险，下肢深静脉超声检查及 TTE 检查有助于及时发现 PTE。
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