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Targeting the MEK5, MEK1/2, and/or Pi3k Pathways Reverses Epithelial to Mesenchymal Transition and Enhances Chemotherapeutic Sensitivity in Breast and Brain Cancers with a Mesenchymal Phenotype

机译：靶向MEK5，MEK1 / 2和/或PI3K途径将上皮细胞转型的上皮性反转，并通过间充质表型提高乳腺癌和脑癌中的化疗敏感性

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作者
Bhatt, Akshita B.;
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作者单位

Duquesne University.;

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授予单位 Duquesne University.;
学科
学位 Ph.D.
年度 2021
页码 228 p.
总页数 228
原文格式 PDF
正文语种 eng
中图分类
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1. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states [J] . T Yoshida, Y Ozawa, T Kimura, British Journal of Cancer . 2014,第6期

机译：甲磺酸依瑞布林通过将表型从上皮-间质转化（EMT）转变为间质-上皮转化（MET）状态来抑制乳腺癌细胞的实验性转移
2. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial|[ndash]|mesenchymal transition (EMT) to mesenchymal|[ndash]|epithelial transition (MET) states [J] . T Yoshida, Y Ozawa, T Kimura, British Journal of Cancer . 2014,第6期

机译：甲磺酸依瑞布林通过将表型从上皮间质转化（EMT）转变为间质|上皮转化（MET）状态来抑制乳腺癌细胞的实验性转移
3. Proteomic analysis of tumor necrosis factor-α resistant human breast cancer cells reveals a MEK5/Erk5-mediated epithelial-mesenchymal transition phenotype [J] . Changhua Zhou, Ashley M Nitschke, Wei Xiong, Breast Cancer Research . 2008,第6期

机译：蛋白质组学分析抗肿瘤坏死因子-α的人类乳腺癌细胞揭示了MEK5 / Erk5介导的上皮-间质转化表型
4. Study of Epithelial-Mesenchymal Transition-associated phenotype in Ovarian Cancer by Quantitative Proteomics [C] . Alfonsina DAmato, Ian Jacobs, Robert L j Graham ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：用定量蛋白质组学研究卵巢癌中皮 - 间充质转换相关表型
5. Autocrine and Paracrine Signaling Regulates Breast Cancer Stem Cells and Epithelial-Mesenchymal Transition in Inflammatory Breast Cancer [D] . Valeta, Amanda. 2016

机译：自分泌和旁碱基信号调节炎症乳腺癌中的乳腺癌干细胞和上皮 - 间充质转换
6. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states [O] . T Yoshida, Y Ozawa, T Kimura, 2014

机译：甲磺酸依瑞布林通过将表型从上皮-间质转化（EMT）转变为间充质-上皮转化（MET）状态来抑制乳腺癌细胞的实验性转移
7. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial–mesenchymal transition (EMT) to mesenchymal–epithelial transition (MET) states [O] . T Yoshida, Y Ozawa, T Kimura, 2014

机译：Eribulin Mesilate通过从上皮 - 间充质转换（EMT）的表型来抑制乳腺癌细胞的实验转移到间充质 - 上皮转换（MET）状态

Targeting the MEK5, MEK1/2, and/or Pi3k Pathways Reverses Epithelial to Mesenchymal Transition and Enhances Chemotherapeutic Sensitivity in Breast and Brain Cancers with a Mesenchymal Phenotype

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