Von

摘要： 利用Von Neumann量子约化熵理论,研究了共振情况下场与原子之间的耦合随时间和强度变化时,A型三能级原子与单模场相互作用系统中量子场熵的演化特性,通过数值计算详细讨论了不同初始光场和耦合系数变化的快慢对量子场熵的影响。结果表明:初始光场统计性质的不同将使系统的量子场熵演化发生较大变化,耦合强度调制函数的变化将改变量子场熵演化曲线的振荡频率,场与原子相互作用的初始阶段是一个逐渐耦合的过程,原子叠加态概率使量子场熵周期性地发生改变。

摘要： The paper searched for raw data about wild-caught fish, where a sigmoidal growth function described the mass growth significantly better than non-sigmoidal functions. Specifically, von Bertalanffy’s sigmoidal growth function (metabolic exponent-pair a = 2/3, b = 1) was compared with unbounded linear growth and with bounded exponential growth using the Akaike information criterion. Thereby the maximum likelihood fits were compared, assuming a lognormal distribution of mass (i.e. a higher variance for heavier animals). Starting from 70+ size-at-age data, the paper focused on 15 data coming from large datasets. Of them, six data with 400 - 20,000 data-points were suitable for sigmoidal growth modeling. For these, a custom-made optimization tool identified the best fitting growth function from the general von Bertalanffy-Pütter class of models. This class generalizes the well-known models of Verhulst (logistic growth), Gompertz and von Bertalanffy. Whereas the best-fitting models varied widely, their exponent-pairs displayed a remarkable pattern, as their difference was close to 1/3 (example: von Bertalanffy exponent-pair). This defined a new class of models, for which the paper provided a biological motivation that relates growth to food consumption.

摘要： BACKGROUND Many advanced hepatocellular carcinoma(HCC) patients are receiving sorafenib treatment. Sorafenib reportedly improves overall survival(OS) significantly in patients with HCC. Prediction of sorafenib response and prognosis in patients with HCC receiving sorafenib treatment are important due to the potentially serious side effects of sorafenib. A disintegrin-like and metalloproteinase with thrombospondin type-1 motifs 13(ADAMTS13) and von Willebrand factor(VWF) are associated with the pathophysiology of liver cirrhosis and HCC through their roles in hypercoagulability; they are also associated with angiogenesis via vascular endothelial growth factor(VEGF). The imbalance between ADAMTS13 and VWF was associated with prognosis of various cancers in patients undergoing chemotherapy.AIM To investigate ADAMTS13 and VWF as potential biomarkers for sorafenib response and prognosis in patients with HCC receiving sorafenib treatment.METHODS Forty-one patients with HCC receiving sorafenib treatment were included in this study. The initial daily sorafenib dose was 400 mg in all patients. ADAMTS13 activity(ADAMTS13:AC), VWF antigen(VWF:Ag), VEGF levels were determined by enzyme-linked immunosorbent assay. Univariate andmultivariate analyses were used to determine predictive factors for sorafenib response and prognosis in patients with HCC receiving sorafenib treatment.RESULTS ADAMTS13:AC was significantly higher in patients with stable disease(SD),partial response(PR), and complete response(CR) than in those with progressive disease(PD)(P < 0.05). In contrast, VWF:Ag and the VWF:Ag/ADAMTS13:AC ratio were significantly lower in patients with SD, PR, and CR than in those with PD(P < 0.05 for both). Multivariate analysis showed that the VWF:Ag/ADAMTS13:AC ratio was the only predictive factor for sorafenib response and ADAMTS13:AC was the only prognostic factor in patients with HCC receiving sorafenib treatment. The patients with a low ADAMTS13:AC(<78.0) had significantly higher VEGF levels than those with a high ADAMTS13:AC(≥ 78.0)(P < 0.05).CONCLUSION The VWF:Ag/ADAMTS13:AC ratio and ADAMTS13:AC are potentially useful biomarkers for sorafenib response and prognosis, respectively, in patients with HCC receiving sorafenib treatment.

摘要： Objective: The objective of this study is to report a case of spinal cord compression, which is a rare complication of neurofibromatosis type 1. Observation: We report the case of a 45-year-old man, which presented a syndrome of thoracic spinal cord compression at the stage of spastic paraparesis. Its installation was gradually over 6 months associated with the inaugural back pain. He had a clinical history of neurofibromatosis type 1 with “Café-au-lait” spots. There were multiple painless nodules under the skin of different size on the chest, forearms and legs. A large isolated nodule, purplish was observed on the chest. The neuro-imaging showed a para-spinal anterior mass expansion inside the spinal canal causing spinal compression at the level of the second and third thoracic vertebra. It extends into the intervertebral foramen of the third and fourth thoracic vertebra leading to a scalloping. A second large heterogeneous left intra-abdominal mass containing cyst areas and calcifications was discovered in imaging. After a spinal decompression with laminectomy of the second and third thoracic vertebra, the reduction of pain and motor recovery was gradual. The large nodule excision was performed. Histology found a plexiform neurofibroma. Excision of the left intra-abdominal mass could not be performed because the patient’s consent had not been obtained. Conclusion: The spinal cord compression is a rare complication of neurofibromatosis type 1. However, it is essential to think about it in front of any spinal cord symptoms or any atypical long term spinal pain.

摘要： We study when exchange rings are von Neumann regular. An exchange ring R with primitive factors Artinian is von Neumann regular, if the Jacobson radical of any indecomposable homomorphic image of R is T-nilpotent, and if any indecomposable homomorphic image of R is semiprime. Every indecomposable semiprimitive factor ring of R is regular, if R is an exchange ring such that every left primitive factor ring of R is a ring of index at most n and if R has nil-property.

摘要： 该文开展了风速风向联合概率分布的研究,以大理地区1971年~2017年47年间的风速日值数据资料为例,选用乘法定理和AL模型两种方法建立该地区风速风向联合概率分布。首先,对各风向以及全风向风速数据的最优概率分布进行研究;其次,分别基于谐波函数和混合von Mises分布对风向的概率密度进行拟合,并进一步基于乘法定理和Angular-Linear(AL)模型推导得出了风速风向联合概率密度函数;最后,对大理地区50年重现期内的极值风速进行预测。研究结果表明:Gumbel分布能更好地描述大理地区的风速分布规律,通过AL模型获得的风速风向联合概率密度函数明显优于基于乘法定理得到的联合概率密度函数;而忽略风向的影响将明显高估大理地区的极值风速。

摘要： 目的评估von Hippel-Lindau(VHL)综合征病人在CT筛查和随访扫描中潜在的电离辐射剂量。材料与方法本研究回顾分析了747例VHL综合征病人[年龄12~83岁,中位年龄(47.6±14.6)岁,女320例(42.8%)]的腹-盆(AP)和胸-腹-盆(CAP)CT扫描,病例来源于美国国立卫生研究院临床中心,收集时间为2009—2015年。

摘要： Timberland investment opportunities in Colombia are expected to increase as a result of the peace agreement recently signed between the Colombian government and the Revolutionary Armed Forces of Colombia. This new socio-political environment may facilitate the expansion of commercial forest plantations on a wider range of site conditions that are currently considered in existing biometric tools. Data from 1119 temporary plots of unthinned, unmanaged, and genetically unimproved Pinus patula plantations in the Antioquia region were combined with a large set of biophysical attributes to identify spatial variation in yield. A wide array of biophysical covariates was explored to characterize the most favorable environmental conditions for the species, and to identify potential explanatory variables to be included in forest yield models. The mathematical form of the model is the von Bertalanffy-Chapman-Richards type, with parameters: asymptote, intrinsic growth rate and allometric constant. The parameters were expressed as linear functions of soil pH, terrain slope, the mean annual temperature to mean annual precipitation ratio, and stand density. The statistical contribution of selected covariates was evaluated using the likelihood ratio test. The model was validated using an independent set of 133 observations. The spatial representation of the model depicts the timber production potential and allows for the identification of the most suitable geographical areas to establish Pinus patula plantations in Antioquia, Colombia. The estimated yield model provides a reliable baseline for timber production, and insight into timberland investments in Colombia.

摘要： 《伟大的指挥家卡拉扬：歌剧间奏曲》是全球首套逐分逐秒解析卡拉扬指挥柏林爱乐乐团演奏的世界经典小品。书里的人物刻画清晰,人物讲述与音乐视听体验相结合,生动详实,魅力无限。传记内容扩展广阔空间,人物业绩与乐团发展并重,拓展多元化研究思路。卡拉扬付出超强的努力和智慧,把音乐、艺术、社会、观众、经济、文化、自然等相互渗透融合,使他的综合能力和个人影响力成为最闪耀、最值得后人借鉴的榜样。

摘要： The objective of the present paper is to introduce a theoretical analysis of bending I-sections after pure bending. The springback values are determined to provide a quantitative method for predicting the springback using von Mises criteria. The analytical methods for the I-section are given for two cases according to the positions of the yield point along the height of the beam. The controlling parameters on the springback of I-sections are studied. The results obtained are quite successful for the prediction of springback for bending I-sections.

摘要： 本发明提供了结合因子VIII的修饰的多肽。所述修饰的多肽包含如SEQ ID NO:3中所示的序列，其中该序列包括在位置1或3处的至少一个修饰，使得修饰的多肽以比包含未修饰的SEQ ID NO:3的参考多肽低至少5倍的解离速率结合因子VIII。

摘要： 本发明涉及基于Von Mises Fisher分布的MIMO信号衰落相关性算法，包括以下步骤：步骤一、建立基于Von Mises Fisher散射体分布的三维空间多天线MIMO模型；步骤二、建立三维空间多天线MIMO天线阵列；步骤三、计算MIMO信号衰落相关性。本发明建立了三维MIMO天线阵列模型，考虑了方位角和俯仰角之间的不独立性，用Von Mises Fisher分布来描述方位角和俯仰角之间的关系。本发明拓展了空间统计信道模型的研究和应用，对评估多天线MIMO系统空时处理算法和仿真无线通信系统提供了有力的工具。

摘要： 本发明提供了结合因子VIII的修饰的多肽。所述修饰的多肽包含如SEQ ID NO:3中所示的序列，其中该序列包括在位置1或3处的至少一个修饰，使得修饰的多肽以比包含未修饰的SEQ ID NO:3的参考多肽低至少5倍的解离速率结合因子VIII。

摘要： 本实用新型提供了一种Von Frey法机械痛敏自动测试装置，包括测痛箱和控制主机，两部分通过有线连接；所述测痛箱包括上室和下室两部分，上室是一个盒状空间，内部通过可拆卸方式包含一个测痛笼；所述测痛笼的下室是一个长方体的箱体空间，包括测痛臂和二维马达臂。该Von Frey法机械痛敏自动测试装置无需人手刺激动物，完全采取机械化方式给予客观标准的刺激强度，且无需操作员弯身低头持续工作，也无需频繁切换手中工具，及时记录，一切通过主机操作，自动刺激、自动记录，使实验结果更准确的同时，极大减轻了实验人员负担。

摘要： 本发明提供了结合因子VIII的修饰的多肽。所述多肽包含截短的von Willebrand因子(VWF)，所述截短的von Willebrand因子包含SEQ ID NO：3中示出的序列或其片段或与其90％相同的序列，其中与SEQ ID NO：3相比所述截短的VWF在选自由以下组成的组的至少一个位置处包含至少一个修饰：S1、S3、L18、V42、S43、K149、N248、S279、V320、T325、Q395和K418。

摘要： 本发明涉及通过在发酵期间分离具有不同分子量的不同vWF多聚体形式来在生物反应器中改进von Willebrand因子(vWF)的重组生产的方法。

摘要： 本发明涉及用于从水溶液中浓缩von Willebrand因子(VWF)的方法，包括通过给水溶液提供钙离子和磷酸盐离子来沉淀VWF和随后借助包含钙络合化合物的水溶液来重新溶解VWF。

摘要： 本发明公开了一种基于von Mises‑Fisher概率模型的网页分类方法，属于互联网及机器学习技术领域。所述方法首先对训练样本进行数据预处理、特征提取和特征筛选后建模，然后将待分类网页的特征向量代入模型中实现最终分类。本发明对所得特征向量进行二范数归一化，在消除文本长度对特征向量影响的同时可为von Mises‑Fisher模型建模做准备；使用von Mises‑Fisher概率模型对文本特征向量进行建模，此模型为首次应用于自然语言处理领域。

摘要： 本发明涉及一种过滤包含von Willebrand因子(VWF)的溶液的方法，所述方法包括(a)提供包含VWF和碱性氨基酸的溶液；和(b)使所述步骤(a)的溶液经历通过孔径小于或等于35nm的过滤器的病毒过滤。

摘要： 本发明提供了结合因子VIII的修饰的多肽。所述多肽包含截短的von Willebrand因子(VWF)，所述截短的von Willebrand因子包含SEQ ID NO：3中示出的序列或其片段或与其90％相同的序列，其中与SEQ ID NO：3相比所述截短的VWF在选自由以下组成的组的至少一个位置处包含至少一个修饰：S1、S3、L18、V42、S43、K149、N248、S279、V320、T325、Q395和K418。