SYNTHETIC PEPTIDE ANALOGS OF LUNG SURFACTANT PROTEIN SP-C OF LUNG SURFACTANT PROTEIN SP-C

摘要

The present invention relates to novel polypeptides of the following Table 1 having the properties of pulmonary activity. These polypeptides can be made in large quantities in very pure form and are as effective as natural lung surfactants. This polypeptide can also be used in the production of pharmaceutical compositions for the treatment of respiratory distress syndrome in premature babies and adults. In the following Sequence Listing 1, A is H or Phe, B is Phe or Trp, and C is Ile, Leu or Ser.;Sequence Table 1