Structure, production, purification and employment of recombinant factors of Actinobacillus pleuropneumoniae virulence for diagnosis and immunoprophylaxis of Actinobacillus pleuropneumoniae in pigs

摘要

the solution involves the design, the production, purification and use of universal vaccines for prophylaxis and control of infections caused by actinobacillus pleuropneumoniae in pigs.the vaccine is the presence of one or more recombinant polypeptide, pripravenu00fdch pru00edsluu0161nu00e9ho gene of actinobacillus pleuropneumonia insercu00ed into expression vector.expression in escherichia coli and subsequent purification.the solution further includes the use of such a recombinant protein as an antigen specific antibody detection umou017enuju00edcu00edch answers as well as their use as specific imunogenu immunisation statuslovu00e9ho species of animals or of experimental animals for the purpose of obtaining highly specific hyperimmune sera.these sera may be used in a wide range of diagnostic methods for the detection of protein urcenu00fdch specific to that procedure, prepared hyperimunnu00edm serumwith the possibility of their subsequent use in the practical diagnostic or experimental investigation.