Sensor for detecting multidrug resistance cancer cell and detecting method of multidrug resistance cancer cell using the same

摘要

The present invention relates to a biosensor for detecting multidrug-resistant cancer cells, a method of manufacturing the same, and an electrochemical detection method. The biosensor is a sandwich type electrochemical immunosensor, which is expressed on the cell membrane of cancer cells, By using a specific monoclonal antibody against glycoprotein (P-gp) as a detection probe and using a non-enzymatic catalyst as a reporter probe, the sensitivity to multi-drug resistant cancer cells can be improved, And it is confirmed that the stability is maintained even for a long period of use. Therefore, it can be used as a biosensor for detecting multi-drug resistant cancer cells for chemotherapy of cancer patients.;