Composition for Improving Skin Conditions or Preventing or Treating Skin Diseases comprising Induced Pluripotent Stem Cell-derived Mesenchymal Stem Cells pre-treated with Interferon-gamma and Exosomes derived therefrom

摘要

The present invention relates to a method for producing induced pluripotency stem cell-derived mesenchymal stem cells (IFNγ-iMSC) pretreated with interferon-gamma; induced pluripotency stem cell-derived mesenchymal stem cells pretreated with interferon-gamma prepared by the method; a pharmaceutical composition for preventing or treating skin diseases comprising culture thereof or exosome (IFNγ-iMSC-exo) isolated therefrom as an active ingredient; and a cosmetic composition for preventing or improving skin diseases. When the composition of the present invention is used, it is possible to provide a composition for skin diseases and a stem cell therapeutic agent, which have an improved immunoregulatory function over conventional mesenchymal stem cells.