Raphanus sativus L. var niger Composition for preventing or treating obesity or fatty liver comprising extract of Raphanus sativus L. var niger as an active ingredient

摘要

The present invention is a black radish ( Raphanus)SativusL. var niger ) relates to a composition for the prevention or treatment of obesity or fatty liver comprising the extract as an active ingredient, the composition activates AMPK (5 'adenosine monophosphate-activated protein kinase) to proliferative cells to fat cells Inhibition of C / EBP-α, C / EBP-δ and PPAR-γ transcription factors involved in the differentiation of the cells and the reduction of the expression of adipose-associated proteins were found to be effective in the prevention or treatment of obesity. In addition, it was confirmed that the composition is effective in preventing or treating fatty liver by inhibiting lipid synthesis in hepatocytes.