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Synthesis and evaluation of 5-(arylthio)-9 H -pyrimido4,5- b indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents

机译：为受体酪氨酸激酶和胸苷合酶抑制剂和作为抗肿瘤剂的合成和评价5-（芳硫基）-9 H-戊酰胺4,5-B吲哚-2,4-二胺

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Nilesh Zaware; Roy Kisliuk; Anja Bastian; Michael A. Ihnat; Aleem Gangjee;
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年度 2017
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1. Synthesis and evaluation of 5-(arylthio)-9H-pyrimido[4,5-b]indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents [J] . Zaware Nilesh, Kisliuk Roy, Bastian Anja, Bioorganic and Medicinal Chemistry Letters . 2017,第7期

机译：5-（芳硫基）-9H-嘧啶[4,5-B]吲哚-2,4-二胺作为受体酪氨酸激酶和胸苷合酶抑制剂和抗肿瘤剂的合成与评价
2. Single Agents with Designed Combination Chemotherapy Potential: Synthesis and Evaluation of Substituted Pyrimido[4,5-b]indoles as Receptor Tyrosine Kinase and Thymidylate Synthase Inhibitors and as Antitumor Agents [J] . Gangjee A, Zaware N, Raghavan S, Journal of Medicinal Chemistry . 2010,第4期

机译：具有设计的联合化疗潜能的单一药物：取代的嘧啶并[4,5-b]吲哚作为受体酪氨酸激酶和胸苷酸合酶抑制剂和抗肿瘤药物的合成和评价
3. The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents [J] . Zhang Xin, Raghavan Sudhir, Ihnat Michael, Bioorganic and medicinal chemistry . 2015,第10期

机译：构象受限的4-取代-2,6-二甲基呋喃[2,3-d]嘧啶作为多靶点受体酪氨酸激酶和微管抑制剂作为潜在抗肿瘤剂的设计，合成及生物学评价
4. EVALUATION OF THE RECEPTOR TYROSINE KINASE INHIBITOR, MASITINIB MESYLATE, IN FELINE VACCINE ASSOCIATED SARCOMA CELL LINES AND HEALTHY CATS [C] . Meighan Daly, Sabina Sheppard, Michael Huelsmeyer, Annual Conference of the Veterinary Cancer Society . 2009

机译：评价受体酪氨酸激酶抑制剂，Masitinib甲磺酸盐，在猫疫苗相关的肉瘤细胞系和健康猫
5. Enantioselective synthesis and reactivity of bicyclobutanes: Strained molecular platforms for 4-, 5-, and 6-membered ring synthesis and rhodium(II)-catalyzed reactions of diazoesters with organozinc reagents. [D] . Panish, Robert A. 2016

机译：双环丁烷的对映选择性合成和反应性：重氮化合物与有机锌试剂的4元，5元和6元环合成和铑（II）催化反应的应变分子平台。
6. Synthesis and Evaluation of 5-(Arylthio)-9H-pyrimido45-bindole-24-diamines as Receptor Tyrosine Kinase and Thymidylate Synthase Inhibitors and as Antitumor Agents [O] . Nilesh Zaware, Roy Kisliuk, Anja Bastian, -1

机译：5-（芳硫基）-9H-嘧啶45-b吲哚-24-二胺作为受体酪氨酸激酶和胸苷酸合酶抑制剂和抗肿瘤剂的合成与评价
7. The design, synthesis and biological evaluation of conformationally restricted 4-substituted-2,6-dimethylfuro2,3-dpyrimidines as multi-targeted receptor tyrosine kinase and microtubule inhibitors as potential antitumor agents [O] . Xin Zhang, Sudhir Raghavan, Michael Ihnat, 2015

机译：构象限制的4-取代的-2,6-二甲基呋喃2,3-D嘧啶的设计，合成和生物学评价为多目标受体酪氨酸激酶和微管抑制剂作为潜在的抗肿瘤剂
8. Egf Receptor Mabs and Chemotherapy/Characterization of Synergistic Interactions Between Cyrotoxic Agents and Inhibitors of the Tyrosine Kinase Growth Factor Receptor Signaling Cascade [R] . Seidman, A. 1999

机译：Egf受体单克隆抗体和化学疗法/ Cyrotoxic剂与酪氨酸激酶生长因子受体信号级联抑制剂之间协同相互作用的表征

Synthesis and evaluation of 5-(arylthio)-9 H -pyrimido4,5- b indole-2,4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents

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