Partial Oxidation of Alkenylsilanes with Ozone: A Novel Stereoselective Approach to the Diol and Triol Derivatives

摘要

The reaction of alkenylsilanes with ozone provides synthetically versatile β-hydroxy or α-formyl silyl peroxides in good yield without normal fission of the C=C bond. The obtained α-formyl silyl peroxides serve as good precursors for the stereochemically defined diol or triol derivatives via nucleophilic addition to the formyl group and reduction of the peroxide moiety.