Polymer-supported synthesis of regioregular head-to-tail coupled oligo(3-alkylthiophene)s

摘要

Solid-phase synthesis of isomerically pure head-to-tail coupled oligo(3-hexylthiophene)s on chloromethylated polystyrene resin has been developed Using novel sequences of iodination and Suzuki cross-coupling reaction, a series up to a dodecamer has been synthesized. Removal of the conjugated oligomers from the solid support as methyl esters, saponification and decarboxylation to the HT-coupled oligo(3-alkylthiophene)s could be effectively achieved.