Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

Ostrov V.F.; EvgenEv M.B.; Murashev A.N.

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Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

机译：用啮齿动物败血症模型研究外源重组人热休克蛋白HSP70的特性

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The protective effects of the exogenous recombinant human heat shock protein with a molecular mass of 70 kDa (rhHSP70) were demonstrated on blood laboratory indices following exogenous injection into Sprague-Dawley rats with induced gram-positive sepsis. Acute toxicity of the protein was studied on CD-1 rats.

机译：在将外源性注射入诱导的革兰氏阳性脓毒症的Sprague-Dawley大鼠体内后，证明了分子量为70 kDa的重组人热休克蛋白（rhHSP70）对血液实验室指标的保护作用。研究了该蛋白对CD-1大鼠的急性毒性。

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《Russian journal of bioorganic chemistry》 |2011年第3期|共4页
作者
Ostrov V.F.; EvgenEv M.B.; Murashev A.N.;
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正文语种 eng
中图分类生物化学;
关键词
acute toxicity; blood biochemical indices; heat shock proteins; lipoteichoic acid; multiorgan dysfunction syndrome; sepsis;

机译：急性毒性;血液生化指标;热休克蛋白;脂蛋白酸;多器官功能障碍综合征;败血症;

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1. Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model [J] . Ostrov V.F., EvgenEv M.B., Murashev A.N. Russian journal of bioorganic chemistry . 2011,第3期

机译：用啮齿动物败血症模型研究外源重组人热休克蛋白HSP70的特性
2. Exogenous Heat Shock Proteins (HSP70) Significantly Inhibit Endotoxin-Induced Activation of Human Neutrophils [J] . M. M. Yurinskaya, M. G. Vinokurov, O. G. Zatsepina, Doklady Biological Sciences . 2009,第Null期

机译：外源热休克蛋白（HSP70）显着抑制内毒素诱导的人类嗜中性粒细胞的活化。
3. Effect of Extracellular Recombinant Human Heat Shock Protein 70 (HSP70) on Protein Pattern Observed after Endotoxin-Induced Macrophage Activation [J] . E. A. Rozhkova, O. G. Zatsepina, M. M. Yurinskaya Molecular Biology . 2011,第2期

机译：细胞外重组人热休克蛋白70（HSP70）对内毒素诱导的巨噬细胞活化后蛋白模式的影响。
4. Material-dependent levels of inducible heat shock protein 70 (Hsp70) in humanplasma and correlation to hemocompatibility [C] . N. Weber, J. Caliebe, G. Ziemer, Annual meeting of the Society For Biomaterials . 2002

机译：血浆中可诱导热休克蛋白70（Hsp70）的物质依赖性水平及其与血液相容性的关系
5. Localization of Heat Shock Proteins HSPA6 (Hsp70B′), HSPA1A (Hsp70-1) and HSPA8 (Hsc70) in Cultured Human Neuronal Cells [D] . Deane, Catherine. 2019

机译：在培养的人神经元细胞中，热休克蛋白HSPA6（HSP70B'），HSPA1A（HSP70-1）和HSPA8（HSC70）的定位
6. Neurotherapeutic activity of the recombinant heat shock protein Hsp70 in a model of focal cerebral ischemia in rats [O] . Maxim A Shevtsov, Boris P Nikolaev, Ludmila Y Yakovleva, 2014

机译：重组热休克蛋白Hsp70在大鼠局灶性脑缺血模型中的神经治疗活性
7. The Optimal Dose of Intraperitoneal Heat Shock Protein (Hsp70) to Prevent Death in Sepsis Mice Model with Multiple Organ Dysfunction Syndrome [O] . IGL Sukamto, Bambang Purwanto, Ambar Mudigdo 2018

机译：腹膜内热休克蛋白（HSP70）的最佳剂量，以防止败血鼠小鼠模型中的多种器官功能障碍综合征

Study of the properties of exogenous recombinant human heat shock protein HSP70 using a rodent sepsis model

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