Synthesis and antiviral evaluation against the Vaccinia virus of new N _1-oxide analogs of 5′-noraristeromycin

Matyugina E.S.; Seley-Radtke K.L.; Andronova V.L.; Galegov G.A.; Kochetkov S.N.; Khandazhinskaya A.L.

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Synthesis and antiviral evaluation against the Vaccinia virus of new N _1-oxide analogs of 5′-noraristeromycin

机译：5'-去甲新霉素的新N _1-氧化物类似物的牛痘病毒合成及抗病毒评价

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摘要

New N _1-benzyl esters of N _1-oxide analogues of 5′-noraristeromycin were synthesized and tested as potential inhibitors of S-adenosyl-L-homocysteine hydrolase in Vaccinia virus-infected cell systems.

机译：合成了5'-去甲诺霉素的N _1-氧化物类似物的新N _1-苄基酯，并在牛痘病毒感染的细胞系统中测试了其作为S-腺苷-L-高半胱氨酸水解酶的潜在抑制剂。

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来源
《Russian journal of bioorganic chemistry》 |2010年第6期|共4页
作者
Matyugina E.S.; Seley-Radtke K.L.; Andronova V.L.; Galegov G.A.; Kochetkov S.N.; Khandazhinskaya A.L.;
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正文语种 eng
中图分类生物化学;
关键词
Antiviral activity in vitro; Inhibitors; N _1-oxide-5′-noraristeromycin derivatives; S-adenosyl-L-homocysteine hydrolase; Vaccinia virus;

机译：体外抗病毒活性;抑制剂;N _1-氧化物-5'-诺拉霉素霉素衍生物;S-腺苷-L-高半胱氨酸水解酶;牛痘病毒;

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1. Synthesis and antiviral evaluation against the Vaccinia virus of new N _1-oxide analogs of 5′-noraristeromycin [J] . Matyugina E.S., Seley-Radtke K.L., Andronova V.L., Russian journal of bioorganic chemistry . 2010,第6期

机译：5'-去甲新霉素的新N _1-氧化物类似物的牛痘病毒合成及抗病毒评价
2. Fluorescence-based antiviral assay for the evaluation of compounds against vaccinia virus, varicella zoster virus and human cytomegalovirus. [J] . Dal Pozzo F, Andrei G, Daelemans D, Journal of Virological Methods . 2008,第1期

机译：基于荧光的抗病毒测定，用于评估针对牛痘病毒，水痘带状疱疹病毒和人巨细胞病毒的化合物。
3. Synthesis and antiviral activity of 7-deazaneplanocin A against orthopoxviruses (vaccinia and cowpox virus). [J] . Arumugham B, Kim HJ, Prichard MN, Bioorganic and Medicinal Chemistry Letters . 2006,第2期

机译：7-脱氮烷普莱诺星A的合成及其对正痘病毒（牛痘和牛痘病毒）的抗病毒活性。
4. Antiviral Activity of Cisplatin Derivatives of Methotrexate Against Vaccinia Virus, Varicella Zoster Virus (VZV), Reovirus ST3, and Herpes Simplex Virus (HSV-1) [C] . Michael R. Roner, Charles E. Carraher Jr., Salima Dhanji PMSE Symposia . 2005

机译：甲氨蝶呤对痘苗病毒，植物疱疹病毒（VZV），reoVirus ST3和单纯疱疹病毒（HSV-1）的抗病毒活性
5. EFFECTS OF CHEMICALLY SYNTHESIZED OLIGODEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES ON VESICULAR STOMATITIS VIRUS PROTEIN SYNTHESIS AND INFECTION (NONIONIC ANALOGS, TRANSLATION, OLIGONUCLEOTIDES, ANTIVIRAL AGENTS). [D] . AGRIS, CHERYL HEATHER. 1986

机译：化学合成的寡脱氧核糖核苷甲磺酸盐对水泡病毒蛋白合成和感染的影响（非离子类似物，翻译，寡核苷酸，抗病毒剂）。
6. Synthesis and Antiviral Activities of Methylenecyclopropane Analogs with 6-Alkoxy and 6-Alkylthio Substitutions That Exhibit Broad-Spectrum Antiviral Activity against Human Herpesviruses [O] . Mark N. Prichard, John D. Williams, Gloria Komazin-Meredith, 2013

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7. Evaluation of carbodine, the carbocyclic analog of cytidine, and related carbocyclic analogs of pyrimidine nucleosides for antiviral activity against human influenza Type A viruses. [O] . Shannon, W M, Arnett, G, Westbrook, L, 1981

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8. Synergistic Antiviral Effects of Ribavirin and the C-Nucleoside Analogs Tiazofurin and Selenazofurin against Togaviruses, Bunyaviruses, and Arenaviruses [R] . Huggins, J. W., Robins, R. K., Canonico, P. G. 1984

机译：利巴韦林和C-核苷类似物Tiazofurin和selenazofurin对Togaviruses，Bunyaviruses和arenaviruses的协同抗病毒作用

Synthesis and antiviral evaluation against the Vaccinia virus of new N _1-oxide analogs of 5′-noraristeromycin

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