Synthesis of 2'-aminometylmorpholino nucleoside analogues containing the 4'-carboxymethyl linker group

摘要

A simple and efficient method has been developed for the preparation of 2'-aminomethylmorpholino-4'-carboxymethyl nucleoside analogues and their 2'-N-Boc-modified derivatives as synthons for obtaining oligomers by peptide synthesis methods.