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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >Independent checking of the delivered dose for high-energy X-rays using a hand-held PC.
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Independent checking of the delivered dose for high-energy X-rays using a hand-held PC.

机译:使用手持式PC独立检查高能X射线的给药剂量。

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BACKGROUND AND PURPOSE: The requirements on the delivered dose in radical radiation therapy are extremely high. The dose should be within a few percent and also delivered with high accuracy in space. Vendors and users have successfully managed to implement radiation therapy systems, which are able to achieve these demands with high accuracy and reproducibility. These systems include computerized tomography scanners, treatment planning systems, simulators, treatment machines, and record and verify systems. More and more common are also computer networks to assure data integrity when transferring information between the systems. Even if these systems are commissioned and kept under quality assurance programs to maintain their accuracy, errors may be introduced. Especially, the human factor is an uncontrolled parameter that may introduce errors. Thus, unintentional changes or incorrect handling of data may occur during clinical use of the equipment. Having an independent dose calculation system implemented in the daily quality assurance process may assure a high quality of treatments and avoidance of severe errors. MATERIALS AND METHODS: To accomplish this, a system of equations for calculating the absorbed dose to the prescription point from the set-up information, has been compiled into a dose-calculation engine. The model is based on data completely independent of the treatment planning system (TPS). The fundamental parameter in the dose engine is the linear attenuation coefficient for the primary photons. This parameter can readily be determined experimentally. The dose calculation engine has been programmed into a hand-held PC allowing direct calculation of the dose to the prescription point when the first treatment is delivered to the patient. RESULTS AND CONCLUSION: The model is validated with measurements and is shown to be within +/-1.0% (1 SD). Comparison against a state-of-the-art TPS shows an average difference of 0.3% with a standard deviation of +/-2.1%. An action level covering 95% of the cases has been chosen, i.e. +/-4.0%. Deviations larger than this are with a high probability due to erroneous handling of the patient set-up data. This system has been implemented into the daily clinical quality control program.
机译:背景与目的:根治性放射治疗对输送剂量的要求非常高。剂量应在百分之几以内,并且还应在太空中以高精度送达。供应商和用户已经成功地实现了放射治疗系统,该系统能够以高精度和可再现性满足这些要求。这些系统包括计算机断层扫描仪,治疗计划系统,模拟器,治疗机以及记录和验证系统。为了在系统之间传输信息时确保数据完整性,计算机网络也越来越普遍。即使对这些系统进行调试并按照质量保证程序进行维护以保持其准确性,也可能会引入错误。特别是,人为因素是可能导致错误的不受控制的参数。因此,在设备的临床使用过程中可能会发生意外更改或不正确的数据处理。在日常质量保证过程中采用独立的剂量计算系统可以确保高质量的治疗并避免严重的错误。材料和方法:为实现此目的,已将用于根据设置信息计算到处方点的吸收剂量的方程式系统编译到剂量计算引擎中。该模型基于完全独立于治疗计划系统(TPS)的数据。剂量引擎中的基本参数是初级光子的线性衰减系数。该参数可以容易地通过实验确定。剂量计算引擎已被编程到手持式PC中,从而可以在首次治疗交付给患者时直接计算到处方点的剂量。结果与结论:该模型已通过测量验证,并显示在+/- 1.0%(1 SD)之内。与最新TPS的比较显示平均差异为0.3%,标准偏差为+/- 2.1%。选择了覆盖95%案件的行动水平,即+/- 4.0%。由于错误地处理了患者设置数据,因此出现较大偏差的可能性很高。该系统已被实施到日常临床质量控制程序中。

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