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首页> 外文期刊>Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology >A simple and robust method for in vivo midline dose map estimations using diodes and portal detectors.
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A simple and robust method for in vivo midline dose map estimations using diodes and portal detectors.

机译:一种使用二极管和门禁探测器进行体内中线剂量图估算的简单而可靠的方法。

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INTRODUCTION: This work investigates the possibility of using a pair of diodes on the beam axis in conjunction with a portal imaging detector to estimate in vivo midline dose distributions, without any additional patient information, related to the external body contour. MATERIALS AND METHODS: In the proposed method, the patient is considered equivalent to a parallelepiped phantom with a thickness z equal to the patient's physical thickness on the field axis with a variable electronic density rho, depending on the water-equivalent thickness. Based on this assumption, if the air gap between portal detector and patient is kept small (within 10-15 cm), the relative exit dose map may be assumed to be equal to the corresponding map measured at the portal detector level by geometrical back projection to the corresponding exit points. The relative exit dose map is then normalized at the on-axis value measured by the exit diode. The entrance dose map is derived by correcting the absolute dose value measured with the diode at the entrance surface by the off-axis ratios. For each pair of entrance and exit doses, the midline dose may be estimated by applying algorithms reported in literature. The method was tested in 6 MV beams using portal film as detector and the Huyskens and Rizzotti algorithms for midline dose estimation. Tests on homogeneous cubic phantoms, homogeneous phantoms with varying thickness symmetrically (simulating head and neck regions) and asymmetrically (simulating abdomen/pelvis region), and a half-sphere phantom with simulating the breast, were performed. Midline doses estimated with the proposed method have been compared with corresponding ones measured by ionisation chamber. RESULTS AND DISCUSSION: Results confirm that the proposed method can be used to estimate midplane dose maps within 2-3% for most clinically suitable situations. For homogeneous symmetrical phantoms the agreement between estimated and measured midline doses decreases with the phantom-portal film distance, the field sizes and the thickness. For homogeneous asymmetrical phantoms the percentage deviations are generally within 3%. Discrepancies larger than 3% (up to 5-6%) are found only for "stressed" irradiation geometries which are not linked with any clinical condition. CONCLUSIONS: The obtained results not only show the accuracy of the proposed method but, due to its simplicity, suggest a rapid clinical implementation of this method in relevant clinical situations such as head-neck, breast and abdomen/pelvis irradiation. Previous investigations which confirmed the possibility of using portal detectors for transit dosimetry in inhomogeneous regions suggest the further exploration of the accuracy and the limits of the proposed method in such cases.
机译:简介:这项工作研究了在射束轴上使用一对二极管结合门禁成像探测器来估计体内中线剂量分布的可能性,而无需任何其他患者信息,而这些信息与体外轮廓有关。材料与方法:在提出的方法中,视患者等效于水等效厚度,认为患者等效于厚度为z的平行六面体幻影,其等效于视场轴上具有可变电子密度rho的物理厚度。基于此假设,如果门禁探测器与患者之间的气隙保持较小(在10-15厘米内),则相对出口剂量图可以假定等于通过几何反投影在门禁探测器水平上测得的对应图。到相应的出口点。然后将相对出口剂量图标准化为由出口二极管测得的同轴值。通过用离轴比校正用二极管在入射表面处测得的绝对剂量值来得出入射剂量图。对于每对进入和离开剂量,中线剂量可以通过应用文献报道的算法来估计。该方法在6 MV光束中进行了测试,使用入口膜作为检测器,使用了Huyskens和Rizzotti算法进行中线剂量估计。对均质立方体模,对称(模拟头和颈部区域)和非对称(模拟腹部/骨盆区域)厚度变化的均质体模型以及模拟乳房的半球形体模进行了测试。用建议的方法估算的中线剂量已与电离室测量的相应剂量进行了比较。结果与讨论:结果证实,对于大多数临床上合适的情况,所提出的方法可用于估计2-3%以内的中平面剂量图。对于均质对称体模,估计和测得的中线剂量之间的一致性随体模-门膜的距离,视野大小和厚度而减小。对于均质的不对称体模,百分比偏差通常在3%以内。仅对于与任何临床状况均不相关的“受压”辐射几何形状,发现差异大于3%(高达5-6%)。结论:所获得的结果不仅表明了该方法的准确性,而且由于其简单性,表明该方法在相关临床情况下(如头颈部,乳房和腹部/骨盆照射)的快速临床应用。先前的研究证实了在不均匀区域中使用门禁探测器进行运输剂量测定的可能性,这表明在这种情况下需要进一步探索所提出方法的准确性和局限性。

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