Pre-operative chemoradiotherapy with UFT and Leucovorin in patients with advanced rectal cancer: A phase II study

Giralt Jordi; Tabernero Josep; Navalpotro Begona; Capdevila Jaume; Espin Eloi; Casado Esther; Manes Anabel; Landolfi Stefania; Sanchez-Garcia Jose Luis; de Torres Ines; Armengol Manel

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Pre-operative chemoradiotherapy with UFT and Leucovorin in patients with advanced rectal cancer: A phase II study

机译：晚期直肠癌患者术前用UFT和白细胞素进行放化疗：II期研究

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Purpose: The aim this study was to determine the pathologic complete response (pCR) rate defined as tumor regression grade 1 (TRG1) and toxicity profile of the combination of high-dose pre-operative radiotherapy and simultaneous UFT/leucovorin (LV) in patients with locally advanced rectal cancer.

机译：目的：本研究的目的是确定患者大剂量术前放疗与同时UFT /亚叶酸钙（LV）联合治疗的病理完全缓解（pCR）率，定义为肿瘤消退等级1（TRG1）和毒性谱局部晚期直肠癌。

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《Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology》 |2008年第3期|共7页
作者
Giralt Jordi; Tabernero Josep; Navalpotro Begona; Capdevila Jaume; Espin Eloi; Casado Esther; Manes Anabel; Landolfi Stefania; Sanchez-Garcia Jose Luis; de Torres Ines; Armengol Manel;
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正文语种 eng
中图分类肿瘤学;
关键词
UFT; Leucovorin; Rectal cancer; Pre-operative treatment; Radiotherapy;

机译：UFT;叶绿素;直肠癌;术前治疗;放疗;

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专利

1. Pre-operative chemoradiotherapy with UFT and Leucovorin in patients with advanced rectal cancer: A phase II study [J] . Giralt Jordi, Tabernero Josep, Navalpotro Begona, Radiotherapy and oncology: Journal of the European Society for Therapeutic Radiology and Oncology . 2008,第3期

机译：晚期直肠癌患者术前用UFT和白细胞素进行放化疗：II期研究
2. A phase I/II study of oral uracil/tegafur (UFT), leucovorin and irinotecan in patients with advanced colorectal cancer. [J] . Mackay HJ, Hill M, Twelves C, Annals of oncology: official journal of the European Society for Medical Oncology . 2003,第8期

机译：在晚期大肠癌患者中进行口服尿嘧啶/替加氟尔（UFT），亚叶酸钙和伊立替康的I / II期研究。
3. Epirubicin, cisplatin and oral UFT with leucovorin ('ECU'): a phase I-II study in patients with advanced upper gastrointestinal tract cancer. [J] . Seymour MT, Dent JT, Papamichael D, Annals of oncology: official journal of the European Society for Medical Oncology . 1999,第11期

机译：表柔比星，顺铂和含亚叶酸（ECU）的口服UFT：I-II期研究在晚期上消化道癌患者中的应用。
4. Phase I/II clinical trials on the effect of weekly paclitaxel (wPTX) and wPTX containing combination regimens for advanced and metastatic gastric cancer -ECRIN group studies [C] . Sakamoto J, Kodera Y, Kobayashi M, International Gastric Cancer Congress . 2009

机译：I / II期临床试验关于每周紫杉醇（WPTX）和WPTX含有晚期和转移性胃癌组合方案的临床试验 - 分泌组研究
5. Pattern of programmed cell death-ligand 1 expression and CD8-positive T-cell infiltration before and after chemoradiotherapy in rectal cancer [D] . Ogura Atsushi, 小倉淳司 2019

机译：直肠癌放化疗前后程序性细胞死亡配体1表达和CD8阳性T细胞浸润的模式
6. Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer [O] . Patrice Cellier, Bernard Leduc, Laurent Martin, 2011

机译：术前放疗联合并发每日替加氟尿嘧啶（UFT）联合亚叶酸治疗局部晚期直肠癌的第二阶段研究
7. Long-term results of a phase II trial of high-dose radiotherapy (60 Gy) and UFT/l-leucovorin in patients with non-resectable locally advanced rectal cancer (LARC) [O] . Vestermark Lene W, Jakobsen Anders, Qvortrup Camilla, 2008

机译：高剂量放疗（60 Gy）和UFT / l-亚叶酸钙蛋白治疗不能切除的局部晚期直肠癌（LARC）的II期临床试验的长期结果

Pre-operative chemoradiotherapy with UFT and Leucovorin in patients with advanced rectal cancer: A phase II study

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