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Radiation treatment of lung cancer-Patterns of Practice in Canada.

机译:肺癌的放射治疗-加拿大实践模式。

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摘要

BACKGROUND AND PURPOSE: To assess the patterns of practice among Canadian radiation oncologists who treat lung cancers. PATIENTS AND METHODS: A questionnaire detailing different aspects of radiation treatment of lung cancer was mailed to all radiation oncologists treating lung cancer in Canada. Seventy-two percent (74/103) of radiation oncologists who treat lung cancer from all 34 Canadian cancer centres replied to the questionnaire. RESULTS: (a) Radiotherapy regimens in Canadian cancer centres are in accordance with several major randomised studies. There is still some variation in treatment practice that may be due to unresolved controversies or limited resources. The most frequently used prescription dose was 40Gy/15f/3w (where f stands for fractions and w stands for weeks) for small cell lung cancer (SCLC) and 60Gy/30f/6w for non-small cell lung cancer (NSCLC). If there were no resource constraints, 30% (22/74) and 20% (15/74) would prefer to use a different dose-fractionation scheme for SCLC and NSCLC, respectively; 95% (70/74) would prefer to use 3D-conformal or intensity-modulated radiotherapy. (b) Among the various modern technologies assessed by respondents, CT (computed tomography) simulator, multi-leaf collimator, on-line electronic portal imaging and PET (positron-emission tomography) scanning were rated the highest in terms of potential patient benefit. Discrepancy between demand and availability of technology was greatest for PET scanning. CONCLUSIONS: Canadian practice in the treatment of lung cancers shows some variations although it is consistent with the trends in the literature. The lack of some modern technologies and human resources is an ongoing concern, especially the lack of PET imaging equipment.
机译:背景与目的:评估治疗肺癌的加拿大放射肿瘤学家的治疗方式。患者和方法:向加拿大所有治疗肺癌的放射肿瘤学家邮寄了一份详细调查肺癌放射治疗不同方面的调查表。来自加拿大所有34个癌症中心的72%(74/103)的放射肿瘤学家对肺癌进行了回复。结果:(a)加拿大癌症中心的放疗方案符合几项主要的随机研究。由于尚未解决的争议或资源有限,治疗实践中仍然存在一些差异。对于小细胞肺癌(SCLC),最常用的处方剂量为40Gy / 15f / 3w(其中f代表分数,w代表数周),对于非小细胞肺癌(NSCLC),最常用的处方剂量为60Gy / 30f / 6w。如果没有资源限制,则分别有30%(22/74)和20%(15/74)的人会选择对SCLC和NSCLC使用不同的剂量分级方案; 95%(70/74)的人更愿意使用3D保形或强度调制的放射疗法。 (b)在受访者评估的各种现代技术中,CT(计算机断层扫描)模拟器,多叶准直仪,在线电子门户成像和PET(正电子发射断层扫描)扫描在潜在的患者获益方面被评为最高。对于PET扫描,技术的需求与可用性之间的差异最大。结论:加拿大在肺癌治疗中的实践显示出一些变化,尽管这与文献中的趋势是一致的。缺乏一些现代技术和人力资源是一个持续的问题,特别是缺少PET成像设备。

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