...
首页> 外文期刊>Nanotechnology >Selective dielectrophoretic manipulation of surface-immobilized DNA molecules
【24h】

Selective dielectrophoretic manipulation of surface-immobilized DNA molecules

机译:表面固定DNA分子的选择性介电电泳操作

获取原文
获取原文并翻译 | 示例
           

摘要

The fabrication of nanoscale molecular devices is becoming increasingly important and research into their fabrication has intensified over the last few years. In particular, the attachment of molecular objects onto various surfaces has attracted considerable attention. Here, we report a multistep surface immobilization procedure, which allows the specific and controlled attachment of very long DNA molecules onto gold electrodes. Further, we report the effect of dielectrophoresis on these surface-bound DNA molecules with respect to amplitude and frequency, and we show that selected surface-immobilized DNA molecules can be manipulated by dielectrophoresis. Finally, we investigated the use of dielectrophoresis in conjunction with the multistep surface immobilization of fluorescently labelled, surface-bound lambda-DNA in a basic data-storage device.
机译:在过去的几年中,纳米级分子器件的制造变得越来越重要,并且对其制造的研究也得到了加强。特别地,将分子物体附着到各种表面上引起了相当大的关注。在这里,我们报告了一个多步骤的表面固定程序,该程序允许将很长的DNA分子特异性和受控地附着到金电极上。此外,我们报道了介电电泳对这些表面结合的DNA分子的振幅和频率的影响,并且我们证明了选择的表面固定的DNA分子可以通过介电电泳进行操作。最后,我们研究了在基本数据存储设备中,介电电泳与荧光标记的表面结合的λDNA的多步表面固定结合使用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号