Defining COPD: from simplistic approach to multilateral assessment of COPD

摘要

Chronic obstructive pulmonary disease (COPD) is a multisystemic pathology, which cannot be characterized, diagnosed or assessed only by the severity of airflow limitation. Thus, it appears there is urgent unmet need of new approach in COPD. In this article we review the most recent multidimensional classification of COPD, based on analysis of functional and physiologic parameters, health status, and risk of exacerbations. A, B, C, D system will permit a more accurate risk stratification of patients. In addition, new trends are presented in assessment of COPD: from phenotypes, multidimensional indices, scale-free networks and diseasome to radical concept of P4 medicine (Personalized, Predictive, Preventive, and Participatory elements).