New tetranuclear macrocyclic complex: Crystal structure, magnetic property and DNA cleavage activity

摘要

A new tetranuclear complex[Cu4L2(bipy)2](ClO4)2·H2O] has been obtained and fully characterized (where bipy = 4,4'-bipyridine, H2L is the macrocycle obtained from [2 + 2] condensation reaction between 2,6-diformyl-4-methylphenol and 1,3-diaminopropane). It exhibits a wheel-like configuration in which two bipy molecules connect two dinuclear [Cu2L]~(2+) units. The magnetic measurement of the complex reveals that there is a strong antiferromagnetic coupling (J= - 383.88 cm~(-1)) between two Cu(II) ions in the macrocyclic unit and ferromagnetic interaction (j' = 10.21) between the Cu(II) ions in two adjacent macrocyclic units. The interactions of the complex with calf thymus DNA were studied by UV-vis and CD spectroscopic techniques and the binding constant of between them is l.74× 10~4 M~(-1).