Hemichorea in a patient with JAK2V617F blood cells

摘要

Chorea has been reported in patients with polycythemia vera (PV). JAK2V617F is a molecular marker used for the diagnosis of PV.1'2 Occasionally, patients have insufficient clinical criteria to establish a diagnosis of PV or only possess some disease features without having overt hematologic manifestations. We present a case of an elderly woman with subacute hemichorea who was found to have normal hematologic profile and JAK2V617F+ hematopoiesis. Hemichorea completely resolved after therapeutic phlebotomy and hydroxyurea therapy.