Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway

Wang Shuo; Song Zhijun; Gong Xiaomei; Ou Chunli; Zhang Wenyu; Wang Jie; Yao Caiyun; Qin Shuangshuang; Yan Bingxiong; Li Qiuping; Wei Kunhua; Hou Xiaoli; Zhou Xiaolei; Miao Jianhua

首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway

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Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway

机译：来自Sophora Tonkinensis Gagnep的氯仿提取物。通过沉默PI3K / AKT / MTOR信号通路抑制鼻咽癌细胞的增殖，迁移，侵袭和促进鼻咽癌的凋亡

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Ethnopharmacological relevance: Sophora Tonkinensis Gagnep. (STG) has been used as a folk medicine for the treatment of different cancers, especially for nasopharyngeal carcinoma, cervical cancer, liver cancer, stomach cancer, lung cancer and leukemia in China. However, the main chemical composition and anticancer mechanism of chloroform extract of STG (CESTG) were still not very clear.

机译：民族药理学相关性：山豆子。在中国，STG已被用作治疗各种癌症的民间药物，尤其是鼻咽癌、宫颈癌、肝癌、胃癌、肺癌和白血病。然而，STG氯仿提取物（CESTG）的主要化学成分和抗癌机理尚不十分清楚。

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《Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs》 |2021年第1期|共13页
作者
Wang Shuo; Song Zhijun; Gong Xiaomei; Ou Chunli; Zhang Wenyu; Wang Jie; Yao Caiyun; Qin Shuangshuang; Yan Bingxiong; Li Qiuping; Wei Kunhua; Hou Xiaoli; Zhou Xiaolei; Miao Jianhua;
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Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Med Univ Affiliated Tumor Hosp Nanning 530021 Peoples R China;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

Guangxi Bot Garden Med Plants Natl Engn Lab Southwest Endangered Med Resources Nanning 530023;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Sophora tonkinensis gagnep.; Nasopharyngeal carcinoma; PI3K/AKT/ mTOR/signaling pathway; Apoptosis;

机译：Sophora Tonkinensis Gagnep。;鼻咽癌;PI3K / AKT / MTOR /信号通路;细胞凋亡;

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7. EG-VEGF silencing inhibits cell proliferation and promotes cell apoptosis in pancreatic carcinoma via PI3K/AKT/mTOR signaling pathway [J] . Yan Xiaogang, Hui Yongfeng, Hua Yongqiang, Biomedicine & pharmacotherapy =: Biomedecine & pharmacotherapie . 2019,第期

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11. Euscaphic acid inhibits proliferation and promotes apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway [O] . Weibo Dai, Pengpeng Dong, Jing Liu, 2019

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机译：LNCRNA TP73-AS1通过抑制KISS1表达和灭活PI3K / AKT / MTOR信号通路的透明细胞肾细胞癌，促进细胞增殖并抑制细胞凋亡

Chloroform extract from Sophora Tonkinensis Gagnep. inhibit proliferation, migration, invasion and promote apoptosis of nasopharyngeal carcinoma cells by silencing the PI3K/AKT/mTOR signaling pathway

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