Iron-Catalyzed Cross-Coupling Reactions:Efficient Synthesis of 2,3-Allenol Derivatives

摘要

Allenes is general and 2,3-allenol derivatives in particular are versatile building blocks for advanced organic synthesis because of the reactivity inherent to their axially chiral backbones.They are usually prepared by S_n2'-type reactions of propargylic substrates with organocopper reagents.