Catalytic Reductive Coupling of Epoxides and Aldehydes:Epoxide-Ring Opening Precedes Carbonyl Reduction

摘要

Transition-metal-catalyzed reductive coupling reactions have attracted considerable interest for several decades since the development of reductive polymerization of carbon monoxide by Fischer and Tropsch.Hydroformylation and the Nozaki-Hiyama-Kishi reaction are other important examples,and in the past decade dozens of nickel- and rhodium-catalyzed reductive coupling reactions have also been described.