An Exceptionally Selective Lead(II)-Regulatory Protein from Ralstonia Metallidurans:Development of a Fluorescent Lead(II)Probe

摘要

Lead contamination is a serious threat to human health and the environment.Lead poisoning is still one of the most common environmentally caused diseases in the world today.Lead levels are typically measured by using atomic absorption spectroscopy or other related instrumental methods.Probes that can provide rapid,on-site evaluation of the lead content of a sample are very valuable for a variety of applications.A primary challenge is to construct a"turn-on"probe that responds to lead(II)ions with a high selectivity over other heavy metal ions.