Minimal Functional Model of Hemostasis in a Biomimetic Microfluidic System

摘要

Biology is functional, and this function both inspires and puzzles. Inspiration from biology has led to the development of biomimetic systems-artificial systems that function by mimicking biology. Biomimetic systems have been successfully created in self-assembly, materials, chemical synthesis, and surface chemistry. They often provide insight into the puzzles of biology, because to develop a biomimetic system, models of biology must be created and tested. In this paper we show how this approach can be extended to a dynamic, nonequilibrium chemical system. We describe a minimal model of hemostasis, then show how this model may be implemented with chemical reactions and used to create a functional microfluidic system that is capable of repairing itself by mimicking hemostasis.