Palladium-Catalyzed [3,3] Sigmatropic Rearrangement of (Allyloxy)iminodiazaphospholidines: Allylic Transposition of C-O and C-N Functionality

摘要

The principle of driving reactions thermodynamically through the conversion of PIII reagents into PV=O products is well established, as exemplified by the Wittig and Mitsunobu reactions, and the [2,3] sigmatropic rearrangement of allyl phosphites into allyl phosphonates. Herein we describe a novel [3,3] sigmatropic rearrangement in which allylic transposition is driven by a PV=N to PV=O interconversion (Scheme 1).