Potential Peptide Carriers: Amphipathic Proline-Rich Peptides Derived from the N-Terminal Domain of γ-Zein

摘要

The ability of certain peptides to cross eukaryotic cell membranes is clearly of interest in the drug delivery field. In recent years, this interest has led to the rapid development of peptide carriers for the delivery of antitumoral, antiviral, or antibiotic drugs, which otherwise would be unable to cross the cell membrane and reach their therapeutic target. Additional advantages of the use of peptide carriers include their low toxicity, accessible synthesis, and high flexibility for modification when attaching peptides or small-molecule drugs as cargoes.