Hydrolysis Triggers Oxidation of a trans Diamine Platinum(II) Anticancer Complex

Ana Maria Pizarro; Vivienne P.Munk; Carmen Navarro-Ranninger; Peter J.Sadler

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Hydrolysis Triggers Oxidation of a trans Diamine Platinum(II) Anticancer Complex

机译：水解引发反式二胺铂（II）抗癌复合物的氧化

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The clinical success of cisplatin (cis-diamminedichloroplatinum(II)) as an anticancer drug has prompted the search for more effective platinum anticancer drugs that circumvent some of its limitations,for example,toxicity and resistance.

机译：顺铂（cis-diamminedichloroplatinum（II））作为抗癌药的临床成功促使人们寻求更有效的铂类抗癌药，以规避其某些局限性，例如毒性和耐药性。

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《Angewandte Chemie》 |2003年第43期|共4页
作者
Ana Maria Pizarro; Vivienne P.Munk; Carmen Navarro-Ranninger; Peter J.Sadler;
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原文格式 PDF
正文语种 eng
中图分类应用化学;
关键词
antitumor agents; hydrolysis; NMR spectroscopy; platinum;

机译：抗肿瘤剂水解核磁共振波谱铂;

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1. Hydrolysis Triggers Oxidation of a trans Diamine Platinum(II) Anticancer Complex [J] . Ana Maria Pizarro, Vivienne P.Munk, Carmen Navarro-Ranninger, Angewandte Chemie . 2003,第43期

机译：水解引发反式二胺铂（II）抗癌复合物的氧化
2. Contrasting Chemistry of cis-and trans-Platinum(II)Diamine Anticancer Compounds:Hydrolysis Studies of Picoline Complexes [J] . Geraldine McGowan, Simon Parsons, Peter J.Sadler Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics . 2005,第21期

机译：顺式和反式铂（II）二胺类抗癌化合物的对比化学：吡咯啉配合物的水解研究
3. Contrasting Chemistry of cis-and trans-Platinum(II)Diamine Anticancer Compounds:Hydrolysis Studies of Picoline Complexes [J] . Geraldine McGowan, Simon Parsons, Peter J.Sadler Inorganic Chemistry: A Research Journal that Includes Bioinorganic, Catalytic, Organometallic, Solid-State, and Synthetic Chemistry and Reaction Dynamics . 2005,第21期

机译：顺式和反式铂（II）二胺类抗癌化合物的对比化学：吡咯啉配合物的水解研究
4. Synthesis, structure and emission property of polymethylene vaulted trans-bis(5- pyrazolylaldiminato)platinum(II) complexes [C] . OLE Ngoc Ha-Thu, NAOTA Takeshi 日本化学会春季年会講演予稿集 . 2018

机译：聚亚甲基拱型反双（5-吡唑基甲醛）铂（II）复合物的合成，结构和排放性能
5. I. THE ELECTROCHEMISTRY OF NITRIC OXIDE AND A NITROUS ACID AT A MERCURY ELECTRODE IN AQUEOUS SOLUTIONS. II. ELECTROCHEMISTRY AND HYDROLYSIS KINETICS OF THE 2,2'-BIPYRIDINE COMPLEXES OF IRON(III) AND IRON(II); ELECTROCHEMICAL KINETIC PARAMETERS FOR SEVERAL IRON COMPLEXES. III. PROTON NUCLEAR MAGNETIC RESONANCE STUDIES OF URANIUM(IV)-ETHYLENE DIAMINETETRAACETIC ACID COMPLEXES IN AQUEOUS (DEUTERIUM-OXIDE) SOLUTIONS. [D] . EHMAN, DEWAYNE LEE. 1969

机译：I.水溶液中汞电极上一氧化二氮和亚硝酸的电化学二。铁（III）和铁（II）的2,2'-联吡啶络合物的电化学和水解动力学；多种铁络合物的电化学动力学参数。三，铀（IV）-水溶液（氧化氘）中铀（IV）-乙撑双氨基乙酸复合物的质子核磁共振研究
6. Hydrolysis of Methionine- and Histidine-Containing Peptides Promoted by Dinuclear Platinum(II) Complexes with Benzodiazines as Bridging Ligands: Influence of Ligand Structure on the Catalytic Ability of Platinum(II) Complexes [O] . Snežana Rajković, Beata Warżajtis, Marija D. Živković, 2018

机译：双核铂（II）配合物与苯并二嗪作为桥接配体促进的蛋氨酸和组氨酸肽的水解：配体结构对铂（II）配合物催化能力的影响
7. Preparation of 3,3-di-tert-butylthiirane trans-1,2-dioxide and its reaction with a platinum(0) complex to give a (disulfenato)platinum(II) complex: Regioselectivity of the oxidation of a related (sulfenato-thiolato)platinum(II) complex [O] . 石井昭彦, イシイアキヒコ, Ishii Akihiko, 2008

机译：3,3-二叔丁基硫杂环丁烷反式1,2-二氧化物的制备及其与铂（0）配合物的反应，生成（二磺基）铂（II）配合物：相关（磺基-硫醇基）铂（II）络合物
8. Crystal and Molecular Structures of a Tricyclic Phosphorus Ester, a Cobalt(III) Macrocyclic Complex and a Trans Coordinated Platinum(II) Compound [R] . Wintergrass, D. J. 1987

机译：三环磷酯，钴（III）大环配合物和反式配位铂（II）化合物的晶体和分子结构

Hydrolysis Triggers Oxidation of a trans Diamine Platinum(II) Anticancer Complex

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