Chiral Dendralenes for Rapid Access to Enantiomerically Pure Polycycles

摘要

Dendralenes are acyclic cross-conjugated oligoalkenes with much synthetic potential.They are particularly attractive precursors for cycloaddition reactions with dienophiles,since they function as multidienes,thereby allowing rapid access to cyclic frameworks.The parent [3]dendralene,for example,can be thought of as a conjoined pair of 1,3-butadienes that can undergo a stepwise sequence of two cycloaddition reactions to form a decalin ring system (Scheme 1,R=H).