Thermally Responsive Polymer Vesicles

摘要

Since lipid vesicles or liposomes were first reported four decades ago,[1] vesicles composed of small surfactant and lipid molecules have been the focus of extensive research as they play an important role in several biological functions including the storage and transportation of small molecules.[2] Cationic liposome-DNA complexes are the most studied nonviral gene-delivery system in humans. However, despite this plethora of information, liposomes still have not attained their full potential as drug and gene carriers partly because of their poor chemical, thermal, and mechanical stability.