Silver-Catalyzed Hydroamination of Siloxy Alkynes

摘要

Transition-metal-catalyzed hydroamination of alkynes has emerged as a valuable method for CN bond formation.[1] While significant progress in this area has been made,[2] several important limitations remain to be addressed. The majority of the previously developed catalytic processes employ highly nucleophilic primary amines that afford the corresponding imines as a result of tautomerization of the initially produced enamides.