Enantioselective Desymmetrization of meso Epoxides with Anilines Catalyzed by a Niobium Complex of a Chiral Multidentate Binol Derivative

摘要

The development of new chiral catalysts for the promotion of asymmetric reactions is one of the most important tasks in organic synthesis.New chiral catalysts must not only mediate reactions with high yields and enantioselectivities,but are also increasingly required to have the ability to recognize the precise structure of substrates.