Adamantaplatensimycin:A Bioactive Analogue of Platensimycin

摘要

Antibacterial resistance is recognized as a worldwide problem in the management of infectious disease.Moreover,during the last two decades the number of new antibacterial agents that have reached the marketplace has decreased whilst resistance to existing antibiotics has increased.Thus,there is an urgent need for new types of antibiotics that exert their activity through novel mechanisms of action.