DNA-Based Barcodes,Nanoparticles,and Nanostructures for the Ultrasensitive Detection and Quantification of Proteins

摘要

Immunoassays are techniques that employ labeled or nonlabeled antibodies for the quantitative assessment of ana-lytes.These techniques have become most popular in clinical and medical research laboratories because they are precise,sensitive,and relatively inexpensive.Increasingly important,however,is the detection of proteins at extremely low concentrations,especially in biofluids containing very low titers of disease markers and in food or environmental samples containing toxic or ineligible proteins.