Enantiomeric Resolution of a Ruffled Porphyrinoid

摘要

Porphyrins have been utilized as platforms for molecularrecognition systems, including examples for chiral substrate recognition. Chiral porphyrins were also used in the enantiocontrol of metalloporphyrin-catalyzed transformations. The synthesis of chiral porphyrins has mainly been through modification of the porphyrin periphery with chiral side chains or by utilizing the chirality of certain atropisomers of ortho-phenyl-substituted meso-tetraarylporphyrins, and chiral resolution was accomplished in some cases. Alternative methods employ chirality transfer from chiral substrates to nonchiral porphyrins.