Excited-State Triple Proton Transfer of 7-Hydroxyquinoline along a Hydrogen-Bonded Alcohol Chain: Vibrationally Assisted Proton Tunneling

摘要

Proton transfer plays a key role in a variety of biological and chemical phenomena such as water autoionization, fast proton diffusion, acid-base neutralization, DNA mutagenesis, enzyme catalysis, and proton pumping through membrane protein channels.[1]-[5] Hydrogen-bonded (H-bonded) chains extending over a long distance have been thought to be particularly effective in mediating the translocation of protons by a Grotthus-type mechanism.[3] However, even in cases of relatively simple and well-characterized systems, the experimental elucidation of the molecular mechanism of proton transfer along H-bonded chains is difficult because the event is intrinsically transient.