Gold(I)-Catalyzed Tandem Cycloisomerization of 1,5-Enyne Ethers by Hydride Transfer

摘要

A novel gold-catalyzed tandem protocol, initiated by hydride transfer in the presence of catalytic (C6F5)(3)PAuCl/AgSbF6, for the formation of fused polycyclic ring systems has been achieved. This tandem reaction provides rapid access to various fused polycyclic species in a single chemical operation, leading to stereospecific formation of two carbon-carbon bonds and three rings.