Synthesis of 2,4,6-Trimethylphenylcalcium Iodide and Degradation in THF Solution

摘要

In contrast to the alkyl- and arylmagnesium halides prepared by Grignard by direct synthesis more than a hundred years ago, the organometallic chemistry of the heavier alkaline-earth metals has received little attention.[1] The main reasons for this are the difficult preparation and the high reactivity of the resulting organometallic compounds. On the one hand, calcium, strontium, and barium metals are not very reactive and must be activated prior to use. On the other hand, the organometallic derivatives tend to cleave ether. Furthermore, owing to the highly ionic metal-carbon bonds these compounds often are insoluble in common organic solvents. In order to overcome these problems several preparative procedures have been developed.