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首页> 外文期刊>Angewandte Chemie >Glc-PC, a New Type of Glucosidic Phospholipid
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Glc-PC, a New Type of Glucosidic Phospholipid

机译:Glc-PC,一种新型的糖苷磷脂

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摘要

Phospholipids such as phosphatidyl choline (PC) are fundamental structural components of biological membranes. In addition to their structural role, they are also important in cellular signal transduction and as regulators of enzyme activity. It hasbeen known for some time that 2-O-alkyl and 2-O-acyl derivatives of 2-lysophosphatidylcholine display both cytotoxic and growth-promoting activities, and this has led to the development of dermatological agents, for instance for the treatment of skin metastases.
机译:磷脂如磷脂酰胆碱(PC)是生物膜的基本结构成分。除了其结构作用外,它们在细胞信号转导中以及作为酶活性的调节剂方面也很重要。一段时间以来,人们已经知道2-溶血磷脂酰胆碱的2-O-烷基和2-O-酰基衍生物既具有细胞毒性又具有促进生长的活性,这导致了皮肤病学试剂的发展,例如用于治疗皮肤。转移。

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