Access to Enantioenriched Organosilanes from Enals and beta-Silyl Enones: Carbene Organocatalysis

摘要

Herein, an efficient route to enantioenriched organosilanes, containing two consecutive stereogenic centers, from enals and beta-silyl enones under carbene organocatalysis is described. Under mild reaction conditions, this transition-metal-free strategy exhibits a broad substrate scope, and excellent diastereo- and enantioselectivity.