Intramolecular Consecutive Dehydro-Diels-Alder Reaction for the Catalytic and Enantioselective Construction of Axial Chirality

摘要

Consecutive thermal and metal-catalyzed dehydroDiels-Alder (DDA) reactions of sulfur-tethered tetraynes, possessing a 1,3-diyne moiety, proceeded efficiently, and axial chirality was achieved for the resulting dibenzothiophenyl moieties Chiral-rhodium catalysis realized a highly enantios-elective synthesis, and transformations into bis(benzocarbazole) derivatives were also achieved.