Single-Face/All-cis Arene Hydrogenation by a Supported Single-Site d(0) Organozirconium Catalyst

摘要

The single-site supported organozirconium catalyst Cp*ZrBz(2)/ZrS (Cp*=Me5C5, Bz=benzyl, ZrS=sulfated zirconia) catalyzes the single-face/all-cis hydrogenation of a large series of alkylated and fused arene derivatives to the corresponding all-cis-cyclohexanes. Kinetic/mechanistic and DFT analysis argue that stereoselection involves rapid, sequential H-2 delivery to a single catalyst-bound arene face, versus any competing intramolecular arene -face interchange.